EvolutionaryScale’s ESM3, a frontier language model family for biology, now available on AWS

EvolutionaryScale’s ESM3 1.4B open source language model is now generally available on AWS through Amazon SageMaker JumpStart and AWS HealthOmics, with the full family coming soon. Amazon SageMaker JumpStart is a ML hub with foundation models, built-in algorithms, and prebuilt ML solutions that can be deployed with just a few clicks. AWS HealthOmics is a purpose-built service that helps healthcare and life science organizations analyze biological data.

EvolutionaryScale, a frontier AI research lab and Public Benefit Corporation dedicated to developing AI for biology’s most complex problems, has released the cutting-edge ESM3 family of models. ESM3 is a biological frontier model family capable of generating entirely new proteins that have never existed in nature. ESM3 can generate proteins based on sequence, structure, and/or functional constraints – a novel "programmable biology" approach. Trained on billions of protein sequences spanning 3.8 billion years of evolution, ESM3 is one of the largest and most advanced generative AI models ever applied to biology.

EvolutionaryScale’s ESM3 1.4B open source model is available in Amazon SageMaker JumpStart initially in US East (Ohio) and in all available AWS HealthOmics regions, except Asia Pacific (Singapore). To learn more, read the blog and press release. To get started with ESM3, visit SageMaker JumpStart website and AWS HealthOmics GitHub repository.